Starting Simponi

Im starting simponi this week along with the methorexate and would like to know how others have found it I was on Embrel but it didnt quite do what it was supposed to do so the Rhuemy changed to Simponi?

I've been on Simponi for a year. Sometimes it works, sometimes it doesn't. I've been on nearly the highest dose a person can take of methotrexate since March, and on prednisone since may. idk, but I do know that simponi alone did not work for me and if I have another flare I'm switching to humira.

I liked the fact that you only had to inject Simponi 1 time a month but it did not work for me after the first few injections so I was switched to Actemra infusions. I tried them for over 6 months and my Rheumy told me we were out of options so I asked him if I could go back to Enbrel and he said yes. I take my 1st injection the 10th of August and I am counting the days. I am so hoping it works for me like it did before! Good Luck with Simponi!

Wendy,

I am on Simponi and I absolutely love it. It works wonderfully on my PsA and I take it without the methotrexate. Just make sure you wait the warm-up time recommended by the package insert - I think it is twenty minutes. Also, the once a month dosage is great! I think you're really going to like it and that it will work well for you.

I took Simponi for a year along with Methotrexate. It did not work for me. I was on Enbrel for 5 years and it eventually stopped working switched to Humira with no success. Just started Remicade and still taking Methotrexate. Fingers crossed that this works

I was on Simponi for over a year both with and without mtx. It didn't do anything so I am back on Enbrel with mtx. At my next appointment if I am still flairing at least monthly my Rheumy says we will try Remicade with mtx. I was concerned about it as it has to be done at the hospital and will take most of the day but after reading about it on this site I am a little excited to give Remicade a try. So many people have reported good results withit. My husband has Weds off so he could accompany me the first couple of times which would be could as am flairing so frequent and I have trouble walking even with a cane. I wish one drug worked for all PsA! It would make everything so much easier.

Thanks for the reply everyone ,I had my first injection today so fingers cross that I get relief,I notice that it does'nt matter what medication anyone is on people will still get flare ups or it works for a while then it stops ,but after going off the medication completely several weeks ago I realised how much "it was doing" even though I was still having troubles ,without any of the medications I was in so much pain from head to the soles of my feet , completely miserable and depressed ,"mind you my little dogs loved it because I was either bed bound or lounge bound when at home and they had me all for themselves, there little faces and their affection kept my spirits up " so I made a promise to myself not to expect to much and any improve would be better than the state I was in and I'm going to appreciate any improvement that will help me to live everyday life even the smallest things ....

Hi Wendy,

I really hope the Simponi works for you :)

I have been taking it for a year now and I found that it has been the most effect drug in treating my PsA. Like you I was on Embrel for a while, but it was not as effective as it needed to be.

I still have litte flare ups and minor problems, but I am nowhere near as bad as I was.

I think you have hit the nail on the head when you say "I'm going to appreciate any improvement that will help me to live everyday life"

Unfortunetly, these drugs will not "Cure" us. They WILL reduce the symptoms and slow the progression, enabling us to live life, if not to the maximum, but to the maximim of out ability :)

Be well,

Louise

Wendy,
I just had my first injection of Simponi today too. I’m hoping it works for both of us. People keep talking about it “working” does that mean a reduction of pain?

It works if there is a reduction in pain and in the number of joints affected by your PsA. With some people it works almost immediately but with many people it takes 3 to six month to receive the full effect.

Thanks- less pain would be a Godsend!

I am 2 and half months in and around my second dose I started getting dizzy and still am almost daily anyone else have this problem?

I haven’t heard of this medicine personally. hope it works for you though!

reading through some of these comments, i dread the thought of having to switch to a different medication. it took the insurance 2 months to ok my enbrel injections (but infusions were covered 100 percent no questions asked…)
and my wifes humira still isn’t all the way approved yet through the insurance. ridiculous.


do both you and your wife have PsA?
youngunn said:

I haven't heard of this medicine personally. hope it works for you though!

reading through some of these comments, i dread the thought of having to switch to a different medication. it took the insurance 2 months to ok my enbrel injections (but infusions were covered 100 percent no questions asked......)
and my wifes humira still isn't all the way approved yet through the insurance. ridiculous.

my wife has RA, sero negative, and i have PsA... what a pair huh? lol

becci214 said:


do both you and your wife have PsA?
youngunn said:

I haven't heard of this medicine personally. hope it works for you though!

reading through some of these comments, i dread the thought of having to switch to a different medication. it took the insurance 2 months to ok my enbrel injections (but infusions were covered 100 percent no questions asked......)
and my wifes humira still isn't all the way approved yet through the insurance. ridiculous.

I tried the Simponi for 3 months but was so nauseous and it made me feel really weird and agitated in the head and unable to concentrate could not live like that so I went off if. I have recently had a bad flare up and my right ankle is so swollen it feels like I have badly sprain and my left foot has flared it it has now been 5 weeks and trying to manage to go to work everyday is very draining and frustrating

There's nothing left for you to try Wendy?