I have had my 3rd monthly injection of Simponi and find that Im feeling quite strange in the head I feel depressed and foggy and not my usual personality and Im not sure if it is a reaction from the Simponi ,has anyone else felt like this
You might try the Simponi support line. Depressed and foggy happen to me as a normal course with my PsA and fibro so I think it is sometimes hard to tell the difference between the disease and the treatment. I am scheduled to start Simponi in 2 weeks but I have had odd random symptoms on Enbrel and Humira. I hope you can find some answers and start feeling better soon.
I would ask your doctor. I've been on Simponi for almost a year and I have never gotten like that after an injection. In fact I usually feel pretty awesome, the opposite of what you're dealing with here. Hope u feel better soon!
I did experience that but from PsA not Simponi. It lasted after I had switched to Enbrel. It wasn't until after I finally had some experience with not being in a flare that I was able to identify it. I wish you hugs and prayers until yours eases up also.
I felt similar after my enbrel shot. Fuzzy, ditzy, like I was on opiates when I wasn't. I've never had this before, so I think it's directly related. Mtx never made me feel this way, nor PsA. I still feel the benefits will be worth the side effects. I hope this validates how you are feeling. I was feeling isolated, as I didn't see other posts describing this.
Thanks everyone for your input. I felt depressed lethargic and foggy with the PsA too when I couldn't do things and had a flare up but this feeling seems different again and don't feel like myself the nausea is not helping as well I feel like I have morning sickness all day long ,I don't want to give up so I will keep doing my trying to work it out
I'm into month 4 on Simponi and have not experienced that side effect YET. I did however have it occasionally with Remicade. I would literally get lost on the elevator that only went between 2 floors. I do get nauseated and dizzy the first 24-48 hours after taking my shot. That first shot I had the dizzys for almost the whole month. Is it helping with your PsA? I'm about to give up on it. It's doing nothing for my PsA and aggravating my P. I told the Rheumy I'd give it through December, but with pustular psoriasis developing on my feet (new since starting Simponi) I'm getting frustrated with it.
It's possible it is working, but you might need to add in something else (MTX or Arava) to help. You could be developing the new P because your disease is flaring. My P gets worse when I flare.
ShutTheFrontDoor said:
It's doing nothing for my PsA and aggravating my P. I told the Rheumy I'd give it through December, but with pustular psoriasis developing on my feet (new since starting Simponi) I'm getting frustrated with it.
ShutTheFrontDoor said:
I'm into month 4 on Simponi and have not experienced that side effect YET. I did however have it occasionally with Remicade. I would literally get lost on the elevator that only went between 2 floors. I do get nauseated and dizzy the first 24-48 hours after taking my shot. That first shot I had the dizzys for almost the whole month. Is it helping with your PsA? I'm about to give up on it. It's doing nothing for my PsA and aggravating my P. I told the Rheumy I'd give it through December, but with pustular psoriasis developing on my feet (new since starting Simponi) I'm getting frustrated with it.
Oh I am definitely flaring. I've been in constant flare since about June which is why we went back to trying biologicals. It's not my first ride in this Rodeo. I've already tried Enbrel, Remicade and Humira, MTX and sulfasalazine, among others I can't remember at the moment, but being those are the most common I get asked about I know I have been there done that :) I've had psoriasis since 98, diagnosed with PsA since 04. It's gotten to the point I am currently on medical leave/temp disability from work until January in hopes that SOMETHING will slow down this flare, but so far not even old standbys like steroid shots are touching it. Not sure why this one is so much more aggressive and bull headed than the rest have been, but I am about resigned to the fact I won't be going back to work and going ahead and filing for LTD and SSD. At anyrate, I wasn't really looking for advice for me as much as saying I had experienced the symptoms with another biological. It is possible that the Simponi is the cause of increased brain fog as many biologicals and DMARDS are known to do that. I just don't have enough experience or historical knowledge of Simponi to know how often that happens.
I'm sorry about your uncontrolled flare. They **really** suck. I hope your doc comes up with some amazing new combo of meds that helps!