Has anyone else been put on Enbrel with Naproxen? I was put on methotrexate in the beginning but had horrible side effects and now my rheumy has me on Enbrel and Naproxen which I have been taking for about 3 months. He also has me on Pepcid for stomach protection. I was wondering how long people have been on Naproxen and is it safe to be on it for a long time. I know it can be hard on the stomach and that is why I am on the Pepcid as well. Also, does anyone else have increased urination with this? I have been drinking a lot more water than I used to but I am having a lot of daytime as well as nighttime frequency. I do have an appointment to see my rheumatologist in a couple of weeks.
Generally speaking, you want to be on blood thinners for the shortest time possible. Typically, once the bio kicks in your doc will slowly remove them.
I am on Enbrel and Celebrex. Celebrex is only a cox2 inhibitor while naproxen is a cox1 and cox 2 inhibitor. There is research showing cox2 inhibitors are less likely to cause gastro. problems.
I have been taking a relatively low dose of celebrex daily for 25 years without a problem.
I've been on one DMARD or another for almost 6 years now, with only slight breaks. I do take prilosec daily whenever I'm on this. The thing is, different people will have different sensitivities. I might be able to take an NSAID at a high dose daily for 20 years, and you might develop a GI bleed, or other complications within a year. Personally, I would like to not be on an NSAID, and occasionally take myself off, and my rheumy supports this. I also use Voltaren gel instead, if there are specific joints that this can be used on.
The increased urination may be related to your bodies way of demanding more water in order to help filter your blood better, and protect your kidneys. Definitely bring this up with your rheumy. They can check your kidney function.
Allan said:
I am on Enbrel and Celebrex. Celebrex is only a cox2 inhibitor while naproxen is a cox1 and cox 2 inhibitor. There is research showing cox2 inhibitors are less likely to cause gastro. problems.
I have been taking a relatively low dose of celebrex daily for 25 years without a problem.
@Allan. Thanks so much for the input. I am so afraid of going off the Naproxen and finding that I have a lot of pain on the Enbrel alone. I am going to definitely talk to my rheumy about the Celebrex. I had so much trouble with the methotrexate that I am even afraid to try lufludamide, which I heard is a cousin to the methotrexate, which my rheumatologist did mention when he felt I could not take the methotrexate.
Allan said:
I am on Enbrel and Celebrex. Celebrex is only a cox2 inhibitor while naproxen is a cox1 and cox 2 inhibitor. There is research showing cox2 inhibitors are less likely to cause gastro. problems.
I have been taking a relatively low dose of celebrex daily for 25 years without a problem.
I also had trouble with meth. but no problems with lefludamide. I currently also take a small dose of the dreaded prednisone with Enbrel and my rheum. says if I deteriorate he will put me on Lefludamide instead (with Enbrel).
the current combination is working well for me.
Bertsdeb said:
@Allan. Thanks so much for the input. I am so afraid of going off the Naproxen and finding that I have a lot of pain on the Enbrel alone. I am going to definitely talk to my rheumy about the Celebrex. I had so much trouble with the methotrexate that I am even afraid to try lufludamide, which I heard is a cousin to the methotrexate, which my rheumatologist did mention when he felt I could not take the methotrexate.
Allan said:I am on Enbrel and Celebrex. Celebrex is only a cox2 inhibitor while naproxen is a cox1 and cox 2 inhibitor. There is research showing cox2 inhibitors are less likely to cause gastro. problems.
I have been taking a relatively low dose of celebrex daily for 25 years without a problem.
Enbrel takes approximately four months to work. If no response, ask for a different biologic. There are lots out there. Celebrex is nice - however it’s expensive and difficult to get approved. Im on 200 mg daily atm.
Hi matanbot. Thanks for the replies. Nice to hear from you. I have been on the Enbrel for almost 3 months. I am seeing a 75% improvement but still having problem in my foot which makes it hard for me to do my exercising. My finger swelling is gone but my toe is still swollen, even with the Naproxen. I see my doctor in a week and will see what he says. So far I do like the Enbrel Like you said, I will see how much better I feel after 4 months. I got nothing but grief from the methotrexate and am afraid of trying lufuldamide. Hopefully I can do well on the Enbrel alone. One can only hope. How long have you taken the Celebrex? Have you ever been on Naproxen. Any differences?
mataribot said:
Enbrel takes approximately four months to work. If no response, ask for a different biologic. There are lots out there. Celebrex is nice - however it's expensive and difficult to get approved. Im on 200 mg daily atm.
I have been on Celebrex for 10 months. Helped with hip, but not much with hands. Celebrex is nice, but it’s not instant. Takes a few weeks to work to really see the results.
It’s nice to see you have had such good results. Before Celebrex I used asprin. I had internal bleeding and stoped all my meds. No such issue with Celebrex.
I have been using Celebrex for years and generally it’s great. I was only taking it when I was feeling aches and a possible flare coming on. If the flare was bad I’d need more but Celebrex totally helps with harsh daily pain. I was taking 200mg once a day unless I was flaring then I took 200 mg twice daily and never any issues however I didn’t use it daily. I’m on MTX now and have only used Celebrex a few times as I’m trying to limit the amount of meds. If I need it I will use it but Celebrex totally has helped me 