I take 20mg of pills at about 8pm, makes for a great nights sleep, as long as I don’t wake up (with a piercing headache - then tramadol is about the only thing that will get me back to sleep, or at least all they’ll prescribe for me!), though it still feels like I’ve only had 5 hours. Like having a hangover the next day - make sure you drink heaps of water, it really does make a difference.
The MTX though, does have different side effects to Enbrel.
There are many wise souls on here, including 2trees (fear the disease, not the meds - hopefully the reason she hasn’t been so active lately is because she’s in remission!), and tntlamb, or just Lamb, who is a statistician ( so he says - and I believe), and is very good at reminding us of the relative side effects of each med (worst NSAID, next MTX, then other DMARDS, lowest side effects, biologics).
I take MTX, because I don’t yet have access to any of the biologics (though that will change next week), and MTX is the only thing (apart from steroids, which I also take lots of - and they aren’t even on the list because they are so bad) to touch it so far.
Anyway, this is a very long way of saying, don’t be more frightened of MTX than the disease, but really, if you are already getting good success with the Enbrel, maybe it’s time to drop the MTX and see what happens?
I’ve had some very major concerns about MTX, but haven’t found a great article that summarized them in somewhat meaningful terms without resorting to gobbledygook, but still had a reasonable scientific basis until just recently. Finally I’ve found it, so here’s the web location;
http://m.rheumatology.oxfordjournals.org/content/47/7/939.full
I still take MTX, but I think it’s very important to have an understanding of your own choices.
If Enbrel works for me, I’ll be dropping MTX like a hot potato!