Methotrexate side effects

Wondering if others taking Methotrexate suffer from stomach upsets such as Acid Reflux or IBS?

Hi Yvonne,
I take MTX by injection once a week. I try to take on Friday after work so I have a couple of days to deal with the nausea and fatigue that are worse for me in the 48 hours after I inject. I also get a strange taste in my mouth after I take the shot. I seem to get by with the jolly rancher cinnamon hot candy…sounds strange, but works for me.

Nope, not me! No significant side effects, and no benefits, unfortunately. The only GI symptom I have is a bad taste in my mouth. My solution is sugar free mints.