I recently had a cat scan done which showed bilateral asymmetric sclerosis of the SI joints. My Rheumy suspects Psoriatic arthritis due to my long history with psoriasis on my skin. He is recommending Enbrel. I am really afraid to do this as I also have a history of lyme. Enbrel is contraindicated in lyme. At this point I'm not sure if this is lyme related or totally separate. I was in treatment for lyme for 1 yr with oral antibiotics. My lyme doctor felt more was needed but my gut had been through enough. I stopped treatment in January. My biggest problem right now is horrible pain around the SI joints. I have tried different antiinflammatories as well as cutting out gluten, starchs and sugar. I have also been trying the antiinflammatory diet. Nothing seems to help. Another practitioner I see is recommending low dose naltrexone. I'm unsure which direction to go in..
What kind of antibiotics were you taking and how long did your lymes go undiagnosed? If you have PsA, then you need to get together with your docs.
Fluoroquinolone family antibiotics (Cipro etc) have just been black labeled because of tendon ruptures also something PsA is known for.
I'm not trying to second guess you lymes doctor, but honestly there isn't much evidence to suggest anything more than two weeks does anthing. Lymes is being blamed for all kinds of things these days. Of course thats mostly on the internet. WERE I you I'd be wanting more information and probably from another source about the lymes. Normaly if you screen for lymes is clear ( whether or not you have had it) you are good to go Many have gotten reactive arthritis from lymes and have been treated with biologics. I wouldn't give up yet.
I wish I had some information for you, but I am not very familiar with Lyme disease. I can offer you my support.
Make sure that your rheum is aware of your concerns with taking Enbrel and find out if there are any other reasonable options. Just because that is the way he is thinking, doesn’t make it written in stone. You might also speak to the doc who treated your for Lyme and see if he has any insight.
This is much easier said than done, but try to minimize your stress, make sure that you are giving yourself time to rest, and learn your limits. Go easy on yourself.
If you need anything, I am here and happy to lend an ear or a shoulder. 
I recently spoke with a doctor and he also recommended low dose naltrexone. I haven't done any research on it yet, but when I read your post, it really caught my attention. Do you know what naltrexone does?
Well said, Grumpy Cat!!
Naltrezone is an opioid antagonist. Its elimintates the "euphoria" Its being used by pain management docs (and a few others) off label in low doses for treatment of Crohn’s disease, irritable bowel syndrome, and fibromyalgia pain. I don't know much about it beyond that. Its used to be used in drug treatment centers but is used less these days, then it was used for smoking cessation replaced by chantix. I understand itr to be pretty darned effective with few side effects when it works.
Spammy said:
I recently spoke with a doctor and he also recommended low dose naltrexone. I haven't done any research on it yet, but when I read your post, it really caught my attention. Do you know what naltrexone does?
Thanks, tntlamb. I looked online and found the website lowdosenaltrexone.org. It sounds like it repairs or improves the immune system to help get rid of autoimmune diseases. I’m going to ask my doctor about it.