Hey has anyone experienced headaches while taking methotrexate? They are really bad and I have even vomited the pain was so bad. I would even go as far as to say these headaches are migraines because of my sensitivity to light and sound and smell. They started the week after I started methotrexate so I am thinking they are related. Any insight would be amazing !
I have been on methotrexate for almost 19 years now. I always feel sick for about 12 hours after my weekly dose headache included, and it has been that way since I started. It is completely normal but in my experience this effect never goes away, it is a strong drug but at least for me the results of taking it are well worth the weekly side effects. I hope this will help you in some way.