Sadly the present focussed research is utterly dire and completely disinterested in comparing biologics. Like you, I wonder why on earth that is.
To sufferers needing biologics it all reeks of incoherency. And yes it does for the sole reason that research scientists always need funding and no big research institute is that interested in patients, they are more interested in making profit.
As for the intelligent, curious, genius researchers of which there are loads, they frankly don’t get paid an awful lot to be able to follow their passion and the interest their seriously magnificent brains are posing. They like us also need to earn enough to put food on the table.
So it’s totally unlikely you’ll find such research. Simply so sadly because there isn’t any.
It’s bizarre there’s none, isn’t it? Blame the funding of research before you blame the scientists though. Venture capitalists the world over fund such research without caring a damn about the result or the patients unless they can make a profit.
Imagine being someone with the wherewithal intelligence wise to research all this but unable to convince the venture capital funders that it will make a profit return. That happens to truly genius scientists every goddamn day sadly.
Comparing biologics in varying scenarios does not make a profit hence there are no such studies of any importance to the type of issues you and your wife need answering.
It’s sadly what we deal with daily in our medical decisions as a patient. No research just try and see and hope for the best. Sigh.
Sadly PsA is never Covid either. There with Covid, the scientific community globally did just the most stunning amazing scientific work. But they’ll never do that for PsA and TB issues or much else frankly.