There were certainly various studies published over the last year or two that DIDN’T link biologics with cancers other than non-melanoma skin cancer. I’m also confused by this study. Firstly it says it was linked to sarcoma, lung cancer, ovarian cancer etc (bottom para of page 1). Then at the bottom of page 2 it says “Malignancies other than non-melanoma skin cancer…were similar in type and number to what would be expected in the general US population.” They need to make their mind up. The final paragraph of page 3, also says the trial was “reassuring.”
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This was posted on another forum, by a PsA patient with stage 4 lung cancer who has been on Stelara. That said, what my Rheumy told me, the biologic just lowers the bodies resistance, the cancer is already present. This theory makes more sense to me, but thought I would share the article.
Hi Jon, I am sorry - we all love shares of research here, and I do really appreciate you posting it (which was part of why I read it so thoroughly).
My understanding is the same as your Rheumy’s, in that we all have the propensity to develop cancer, and we actually have natural immune cells that kill cancers - in theory, some immunosuppressants can make that harder.
Luckily, unless you are a young male with Crohns taking biologics, and have B cell cancer, then so far the chances of the biologics having an impact seem to be nothing, or at worst, small - but you are right - it needs to be constantly watched.
I’m on the knife edge between a begnign cancerous state, and asymptomatic multiple myeloma (terminal) myself, so I do like to hear every single study - even if I later decide the methodology is a bit cr*p 
Thankyou
Hi Jon_Sparky. Just read through this thread and glad to see you have had some very good results with the surgery and other procedures. Scary stuff! Oh, and avoiding the norovirus—now that’s the icing on the cake!!!
I had avoided this discussion earlier as cancer scares me and I didn’t want to read something that would cause me to worry more than I already do, but it’s always good to hear about positive outcomes and, from what I’ve gathered, cancer risk doesn’t increase from being on a biologic.
I guess being a sun worshiper is the culprit. I wonder how much sun is too much? I use the tanning beds every spring and usually lay out in the sun a few times during the summer. The psoriasis on my legs (mostly only my right leg) is so ugly I wouldn’t be able to wear shorts or a bathing suit at the beach. I’m wayyyyy too self-conscious about it!
My daughter asked me to go on vacation with her family (5 kids) in March…of course we’ll go south to either Florida or AZ, and of course, I’ll tan beforehand so my legs look “acceptable”. So vain, I know! But each year I’m getting more and more concerned that one of these times I’ll develop skin cancer, and there’s no turning around from that.
It sucks, tho, when you can’t go in a public swimming pool because you have red patches all over your legs that look contagious! And, you can’t go around explaining to everyone not to worry—it’s psoriasis and they won’t catch it!
Anothere sinister thing about this, my Rheumy said that sinse inflammation is the culprit in causing a lot of cancers, when biologics were first introduced, a lot of patients all ready had cancer started, because of the chronic inflammation, so when the biologic comprimissed the immune system, they blamed the biologic for causing the cancer.
Sorry to hear that you have myeloma, no fu. My previous Rheumy, did a typo in her report and put high IgA protein instead of IgM, and thought I had Myeloma, after getting all the bone scans I went to the Hematologist, he said I didn’t need all the imaging, that IgM was actually another blood cancer called Waldenström’s macroglobulimia, it is a mild NHL, that can be treated with medication, right now I am just getting monitored. A study found a link of this cancer to Inflammation, so I am a example, that if one delays biologics, it can actually give you cancer.
With my nordic white skin and blue eyes, I have always been suseptable to skin cancer. We used to use baby oil for a better tan!
They do make those full body swimsuits made from spandex, then you wouldn’t be in the sun, but could swim.
I was fortunate with Ps, only have it on my scalp and rear, Remicade has eliminated it, so much so that my new Rheumy didn’t believe that I had it! Luckily I have photos of at least my scalp, when it was bad.
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What Jon has said is reflected in the articles I read earlier in the year: the reason why people on biologics have more chance of cancer is due to their illness and not the biologic.
Hi Jon, sorry I must have written that very poorly too late last night - I’m still very much in the begnign state (its weirdly arbitrary though) and am just getting monitored myself. I may well never get frank myeloma, or at least die of domethimg else first!
I was just saying it’s great that you are sharing the articles- exactly as both you and Darinfan said, because of a little bit of extra susceptibility I’m sure there are lots of people who appreciate it.
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I guess it is like me, but you have a IgA protein they are monitoring, I have IgM protein, they did confirm the cancer with my, it is in my bone marrow, took it from my iliac bone, but it is just a couple of cells, interesting, as this is where I have a lot of inflammation, the SIJ. Even though they said it was “normal”… I tell people this is one of the good cancers, everything elsw will kill me first.
Yep - I’m sure something else will kill me first too! I had those silly cells in the bone marrow too - but right at the threshold (10%) to do anything about them.
See my other post, but I’m pretty optimistic nothing will come of it. I do find it kind of curious so many of us can be wandering about with “just a little bit” of cancer that has little to no impact though - it has certainly changed my understanding of how the body works!
Doesn’t look too bad at all. And your eye is amazing!
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Thanks, the Picato went well too, just peeled for 2 weeks, much easier then the Chemo creme 5FU…
Glad to see another guy with a support cat! I have/had several. THey are great friends and always seem to know when you need a hug.
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Is there a Message in the name of the Chemo creme…? 
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I thought it fit the creme, after 5 weeks of the stuff it is capital letters FU and the 5 for the 5 weeks! 
Decided to hit a few of the spots that didn’t clear up, with the 5F___ __U Chemo cream. Mainly the spots are above my eyebrows, and on my nose, if this doesn’t clear them up, it is off for another biopsy. I guess they could raise my eyebrows some, that way it will adjust for the receding hairline!
You could just grow the eyebrows out and do a comb over…
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Little Trump doos? 
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Your Kittie is your best medicine. I have two that never leave my side until I feel better.
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Yes, good care givers, just wish he wouldn’t wake me up at 3:30am to tell me he loves me…
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