Speaking of prostaglandins – I have read that marijuana is loaded with these and some argue that it is this property that makes it promising or work.
Ok, so back on topic. MMJ is not legal in my state, so I can’t comment on that.
What I can comment on though, is that the best treatment is TREATMENT. The type that slows disease progression.
I do not dispute the quality of life argument - but after 9 months on numerous DMARDs that did next to nothing, plus steroids that made me just functional and gave me osteopaenia at the age of 36, and the whole time on codeine, just to stop me crying, the relief I felt when I got a DMARD (yes a biologic) that worked!
The fog lifted, I was totally disinterested in pain meds, I was me again. Persist in getting real treatment- really do. There is nothing better for quality of life than that 
Agreed but treatment is dynamic and results vary for all of us. There is a balance and I believe treating symptoms is not irrelevant relating to life function.
Well, hopefully some day we can get some good studies relating to medical marijuana, pain, and inflammation. The prostaglandin thing is interesting. I read some academic paper about it. I can’t recall but it was interesting. Here is some food for thought.
http://online.liebertpub.com/doi/full/10.1089/can.2017.0017
https://www.researchgate.net/publication/233799248_Prostaglandins_and_Rheumatoid_Arthritis
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Well, my evening just got ruined. My PsA has progressed to psoriatic arthritis mutilans - yes, the PsA has literally eaten away bone in my ankles, feet, knees, neck, hands, shoulders and mostly seriously, my spine’s L4, L5 and S1. Every disc in my back shows signs of DDD with either compression, bulging or rupturing. My mobility is very limited. My walking is now at a snail’s pace for 100 ft. max. The pain that I live with - well, I know the meds don’t help a lot but I can’t imagine life without them. I have to live this life day by day. If I looked long term very often, I would find a permanent way to get out of this misery. I’ve worn out the biologics - I have used 8 different ones over the last 12 years. I do take a DMARD - Arava - but I don’t see much difference. Chronic, unrelenting pain is terrible. Please don’t take what little bit of hope I have for the days to come.
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I am so sorry to hear this for your sake. That is what I fear. I understand what you are saying about pain meds. At this point I cannot imagine life without them. I try to be realistic and I would love to ditch them, but it just ain’t happening for me. I sure hope I get there but nothing is certain. I can relate to what you say about long term. It is certainly depressing. Hang in there. I hope you find comfort. Unless you walk the road it is hard to know where it goes and how hard it is.
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Good to know thx for the explanation
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