I ask because I have noticed one thing that I wasn't even thinking about when I went on MTX and all the others....
My libido.
Before the drugs, the pain was so terrible that intimacy was the last thing on my mind. Now, despite the fatigue and fogginess, I have a lot less pain and I am on sick leave so I'm not exerting myself and forcing the pain out. With all that, it seems that suddenly my libido came back. It's one ray of light in all of this. ;)
Another "side effect" is a cleaner, more organized house - not because I do more, but because I CARE more. When in extreme pain, my standards drop dramatically.