# Horrible week!
**URL:** https://discussion.livingwithpsoriaticarthritis.org/t/horrible-week/740
**Category:** General
**Created:** [July 28, 2012, 4:34pm UTC](https://discussion.livingwithpsoriaticarthritis.org/t/horrible-week/740 "2012-07-28T16:34:08Z")
**Posts on this page:** 3
**Page:** 1
### Author:  [@JoJo](https://discussion.livingwithpsoriaticarthritis.org/u/JoJo)
#### Post date: [July 28, 2012, 4:34pm UTC](https://discussion.livingwithpsoriaticarthritis.org/t/horrible-week/740/1 "2012-07-28T16:34:08Z")
Had terrible joint pain on wednesday the terrible nuaseau on thursday (possibly due to my weekly dose of methotrexate) Woke up on friday morning with a cold then had terrible stomach pain for about ten hours costing me a trip to the emergency room. Doctors says that the pain is due to the anti-inflammatories being too strong for my stomach.Any suggestions with regards to anti-inflammatory meds?
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### Author:  [@dani7865](https://discussion.livingwithpsoriaticarthritis.org/u/dani7865)
#### Post date: [July 28, 2012, 7:13pm UTC](https://discussion.livingwithpsoriaticarthritis.org/t/horrible-week/740/2 "2012-07-28T19:13:47Z")
Hey JoJo...I have had alot of problems with these things too. Celebrex gave me an ulcer in the past, which the COX2 inhibitors are not supposed to do. I could not take them at all for many years, but recently have had some success with Meloxicam, HOWEVER, I have to make sure I take it RIGHT AFTER I eat, and I mean RIGHT AFTER! For some reason, if I don't take it on my FULL stomach, I still get stomach upset. It provides me with a bit of relief but has not been the strongest of the anti inflammmatories that I have taken, but it has been the only one that I have been able to take at all since I got the ulcer from Celebrex. You could ask your doctor about a stomach protector to take in conjunction with the anti-inflammatories, ie, pantoloc, this works for some people.
Hope this helps.
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### Author:  [@Rebel\_mom](https://discussion.livingwithpsoriaticarthritis.org/u/Rebel_mom)
#### Post date: [July 28, 2012, 11:13pm UTC](https://discussion.livingwithpsoriaticarthritis.org/t/horrible-week/740/3 "2012-07-28T23:13:38Z")
Yes a stomach protector is a must! That is the first med i take in the morning. it works best on an empty stomach one hour before meals