# Medications

**URL:** https://discussion.livingwithpsoriaticarthritis.org/c/general/medications/10.md

[Latest](https://discussion.livingwithpsoriaticarthritis.org/latest.md) · [Categories](https://discussion.livingwithpsoriaticarthritis.org/categories.md)

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## [About the Medications category](https://discussion.livingwithpsoriaticarthritis.org/t/about-the-medications-category/16)

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**Author:** [@system](https://discussion.livingwithpsoriaticarthritis.org/u/system)\
**Replies:** 0\
**Last updated:** [September 7, 2016, 9:38am UTC](https://discussion.livingwithpsoriaticarthritis.org/t/about-the-medications-category/16 "2016-09-07T09:38:34Z")

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Want specific information or others experiences with a specific medication? This is the place for it.

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## [Biologics](https://discussion.livingwithpsoriaticarthritis.org/t/biologics/3147)

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**Author:** [@Dini](https://discussion.livingwithpsoriaticarthritis.org/u/Dini)\
**Replies:** 50\
**Last updated:** [March 30, 2026, 1:07pm UTC](https://discussion.livingwithpsoriaticarthritis.org/t/biologics/3147 "2026-03-30T13:07:42Z")

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Hi I'm wondering about everyone's experience on biologics and the brand of biologic they are taking. I still need to call and see if my health plan will cover me for biologics. I am also contemplating participating in a …

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## [Biologics running out of steam](https://discussion.livingwithpsoriaticarthritis.org/t/biologics-running-out-of-steam/11623)

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**Author:** [@Amos](https://discussion.livingwithpsoriaticarthritis.org/u/Amos)\
**Replies:** 42\
**Last updated:** [May 1, 2025, 8:50am UTC](https://discussion.livingwithpsoriaticarthritis.org/t/biologics-running-out-of-steam/11623 "2025-05-01T08:50:52Z")

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For the last 2 months, when I’m about a week away from my next Taltz injection, (every 28 days) I start to flare. Increased pain and morning stiffness that takes way longer to fade. Do some biologics run out of steam bef…

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## [Help with meds](https://discussion.livingwithpsoriaticarthritis.org/t/help-with-meds/11549)

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**Author:** [@Freyza131](https://discussion.livingwithpsoriaticarthritis.org/u/Freyza131)\
**Replies:** 5\
**Last updated:** [March 28, 2024, 7:13am UTC](https://discussion.livingwithpsoriaticarthritis.org/t/help-with-meds/11549 "2024-03-28T07:13:48Z")

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Hi all you lovely people. I am looking for some advice. I have tried methotrexate tablets - bad side effects. They moved me to the injections - which pretty much ruined my life due to the crippling nausea. Went to the …

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## [Mtx wearing off](https://discussion.livingwithpsoriaticarthritis.org/t/mtx-wearing-off/11544)

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**Author:** [@Rebel\_mom](https://discussion.livingwithpsoriaticarthritis.org/u/Rebel_mom)\
**Replies:** 6\
**Last updated:** [March 6, 2024, 6:43pm UTC](https://discussion.livingwithpsoriaticarthritis.org/t/mtx-wearing-off/11544 "2024-03-06T18:43:53Z")

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my rhuemy started me on mtx to help with the skyrizi. i take the mtx on a sunday but it seems by saturday the joints and body are telling me that the medicine has worn off. would an increases help one or is it normal f…

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## [Covid-19 and continuing biologics](https://discussion.livingwithpsoriaticarthritis.org/t/covid-19-and-continuing-biologics/11540)

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**Author:** [@MDKM](https://discussion.livingwithpsoriaticarthritis.org/u/MDKM)\
**Replies:** 3\
**Last updated:** [February 21, 2024, 7:12pm UTC](https://discussion.livingwithpsoriaticarthritis.org/t/covid-19-and-continuing-biologics/11540 "2024-02-21T19:12:14Z")

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Hi friends, I have a quick question. I tested positive for the first time on Friday with Covid-19, and I am due for my next abrilada (biosimilar of humira) injection tomorrow. Can I take it? I don’t have a fever and ha…

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## [Folks who have tried many biologics?](https://discussion.livingwithpsoriaticarthritis.org/t/folks-who-have-tried-many-biologics/4571)

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**Author:** [@Piganli](https://discussion.livingwithpsoriaticarthritis.org/u/Piganli)\
**Replies:** 30\
**Last updated:** [December 15, 2023, 5:35am UTC](https://discussion.livingwithpsoriaticarthritis.org/t/folks-who-have-tried-many-biologics/4571 "2023-12-15T05:35:46Z")

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Who out there has been on most or many biologics along the way? When do you decide to stop trying another biologic? I'm flaring again, enough to have the rheumy probably move me yet again. In four years I've been on En…

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## [Anyone here on skyrizi? i](https://discussion.livingwithpsoriaticarthritis.org/t/anyone-here-on-skyrizi-i/11337)

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**Author:** [@Rebel\_mom](https://discussion.livingwithpsoriaticarthritis.org/u/Rebel_mom)\
**Replies:** 3\
**Last updated:** [November 19, 2023, 4:42pm UTC](https://discussion.livingwithpsoriaticarthritis.org/t/anyone-here-on-skyrizi-i/11337 "2023-11-19T16:42:32Z")

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anyone here on skyrizi?

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## [Just changed to Humaria](https://discussion.livingwithpsoriaticarthritis.org/t/just-changed-to-humaria/11331)

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**Author:** [@Rebel\_mom](https://discussion.livingwithpsoriaticarthritis.org/u/Rebel_mom)\
**Replies:** 36\
**Last updated:** [November 15, 2023, 11:33pm UTC](https://discussion.livingwithpsoriaticarthritis.org/t/just-changed-to-humaria/11331 "2023-11-15T23:33:55Z")

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Hello,… I have just been switched to my second biologic after 12 years of being on Enbrel. Well I am going on six weeks on this new one and I feel worse than I did at the end of Enbrel. Very sore, tight, slight pain an…

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## [How to know when your "drug of choice" is working](https://discussion.livingwithpsoriaticarthritis.org/t/how-to-know-when-your-drug-of-choice-is-working/11323)

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**Author:** [@Northernelf](https://discussion.livingwithpsoriaticarthritis.org/u/Northernelf)\
**Replies:** 9\
**Last updated:** [August 28, 2023, 10:18pm UTC](https://discussion.livingwithpsoriaticarthritis.org/t/how-to-know-when-your-drug-of-choice-is-working/11323 "2023-08-28T22:18:40Z")

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Currently getting treated for a lovely UTI (by some awesome antibiotics that worked almost immediately) - guess that shouldn’t be a surprise since Rinvoq has knocked my white blood cells, etc. right down. Anyway…nothing …

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## [Current COVID Vaccine - Rinvoq (and other meds)](https://discussion.livingwithpsoriaticarthritis.org/t/current-covid-vaccine-rinvoq-and-other-meds/11289)

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**Author:** [@Northernelf](https://discussion.livingwithpsoriaticarthritis.org/u/Northernelf)\
**Replies:** 9\
**Last updated:** [May 13, 2023, 8:19am UTC](https://discussion.livingwithpsoriaticarthritis.org/t/current-covid-vaccine-rinvoq-and-other-meds/11289 "2023-05-13T08:19:05Z")

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Darn it !!! So I was reading another forum and apparently you aren’t supposed to keep taking Rinvoq/JAK inhibitors if you get the latest COVID vaccine - you should take 7 days off. Didn’t think to look that up - I had a…

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## [Combining Otezla with Taltz](https://discussion.livingwithpsoriaticarthritis.org/t/combining-otezla-with-taltz/10546)

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**Author:** [@sbender](https://discussion.livingwithpsoriaticarthritis.org/u/sbender)\
**Replies:** 8\
**Last updated:** [December 25, 2022, 10:44pm UTC](https://discussion.livingwithpsoriaticarthritis.org/t/combining-otezla-with-taltz/10546 "2022-12-25T22:44:40Z")

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Hi All, Starting with Otezla as DMARD alongside the Taltz injection. Arava was giving nerve problems in my feet. Very exited about this as I was on Otezla before and it worked well. Will keep ye posted how it works ou…

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## [Humira: Have you been more prone to illnesses?](https://discussion.livingwithpsoriaticarthritis.org/t/humira-have-you-been-more-prone-to-illnesses/4531)

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**Author:** [@Guinnie](https://discussion.livingwithpsoriaticarthritis.org/u/Guinnie)\
**Replies:** 20\
**Last updated:** [August 4, 2022, 2:40pm UTC](https://discussion.livingwithpsoriaticarthritis.org/t/humira-have-you-been-more-prone-to-illnesses/4531 "2022-08-04T14:40:28Z")

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I start my first dose of Humira tomorrow - first experience with a biologic - and I understand it makes you more susceptible to infection. Do you take precautions to avoid illnesses? Is it like people who are on chemothe…

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## [Reducing Dose of Methotrexate](https://discussion.livingwithpsoriaticarthritis.org/t/reducing-dose-of-methotrexate/10474)

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**Author:** [@FatJoints](https://discussion.livingwithpsoriaticarthritis.org/u/FatJoints)\
**Replies:** 41\
**Last updated:** [August 4, 2022, 2:30pm UTC](https://discussion.livingwithpsoriaticarthritis.org/t/reducing-dose-of-methotrexate/10474 "2022-08-04T14:30:33Z")

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Hi all, newbie here. I’m interested to learn other experiences of lowering methotrexate dose (or any other meds) Back in 2017 I had my first ever flare and it was the first time I realised I had psa. Most of my joints…

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## [Tremfya - It worked for me](https://discussion.livingwithpsoriaticarthritis.org/t/tremfya-it-worked-for-me/11125)

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**Author:** [@Keith](https://discussion.livingwithpsoriaticarthritis.org/u/Keith)\
**Replies:** 1\
**Last updated:** [July 30, 2022, 3:24pm UTC](https://discussion.livingwithpsoriaticarthritis.org/t/tremfya-it-worked-for-me/11125 "2022-07-30T15:24:47Z")

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Trust me I know that not everyone has the same outcomes on the same drugs, I failed on all of them. It has been a year on Tremfya, I can stand up and walk without pain I have actual toe and fingernails, and those deep c…

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## [Evusheld - has anyone had it yet](https://discussion.livingwithpsoriaticarthritis.org/t/evusheld-has-anyone-had-it-yet/11126)

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**Author:** [@Aldb](https://discussion.livingwithpsoriaticarthritis.org/u/Aldb)\
**Replies:** 9\
**Last updated:** [July 26, 2022, 6:43pm UTC](https://discussion.livingwithpsoriaticarthritis.org/t/evusheld-has-anyone-had-it-yet/11126 "2022-07-26T18:43:46Z")

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Hi - My doctor is suggesting I take the emergency use authorized Evusheld which is two does of antimicrobal antibodies to help prevent COVID. It is for folks who are immunocompromised. Has anyone had this vaccine yet?…

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## [Medication Vent](https://discussion.livingwithpsoriaticarthritis.org/t/medication-vent/10758)

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**Author:** [@Suzanne\_H](https://discussion.livingwithpsoriaticarthritis.org/u/Suzanne_H)\
**Replies:** 5\
**Last updated:** [July 25, 2022, 2:38pm UTC](https://discussion.livingwithpsoriaticarthritis.org/t/medication-vent/10758 "2022-07-25T14:38:47Z")

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It has been a long time since I have checked in, but I need to vent. I have taken Remicade since 2013 and have had great results. I’ve also had the same insurance for years. Remicade has always been covered. In October …

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## [Adding Methotrexate for the First Time](https://discussion.livingwithpsoriaticarthritis.org/t/adding-methotrexate-for-the-first-time/10522)

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**Author:** [@amielynn38](https://discussion.livingwithpsoriaticarthritis.org/u/amielynn38)\
**Replies:** 36\
**Last updated:** [July 22, 2022, 8:52pm UTC](https://discussion.livingwithpsoriaticarthritis.org/t/adding-methotrexate-for-the-first-time/10522 "2022-07-22T20:52:17Z")

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Hello all and Happy New Year!! I saw my rheumatologist today and I am starting on a 10 mg dose of methotrexate each week. Though I am familiar with the medication and some of the side effects I would appreciate any reco…

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## [Xeljanz cancer and cardiac risks](https://discussion.livingwithpsoriaticarthritis.org/t/xeljanz-cancer-and-cardiac-risks/10603)

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**Author:** [@DMaraJade](https://discussion.livingwithpsoriaticarthritis.org/u/DMaraJade)\
**Replies:** 9\
**Last updated:** [June 25, 2022, 3:54am UTC](https://discussion.livingwithpsoriaticarthritis.org/t/xeljanz-cancer-and-cardiac-risks/10603 "2022-06-25T03:54:01Z")

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I am crushed. This is the one that actually helped me after being on Mtx, Enbrel, Humira, Cosentyx, Remicade, and Otezla - all of those had minimal to zero results. Now I find that there is an article from Feb 2021 abou…

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## [Sunburn help](https://discussion.livingwithpsoriaticarthritis.org/t/sunburn-help/11075)

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**Author:** [@Freyza131](https://discussion.livingwithpsoriaticarthritis.org/u/Freyza131)\
**Replies:** 10\
**Last updated:** [May 26, 2022, 9:24pm UTC](https://discussion.livingwithpsoriaticarthritis.org/t/sunburn-help/11075 "2022-05-26T21:24:07Z")

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Hi all. It’s been a long time since I have posted. I have now been on methotrexate for a few months. Started on tablets but now on injections. I have just been away for a few days in Ibiza. On the first day I used sun …

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## [Cosentyx - I think it is working!](https://discussion.livingwithpsoriaticarthritis.org/t/cosentyx-i-think-it-is-working/10863)

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**Author:** [@Randomgirl](https://discussion.livingwithpsoriaticarthritis.org/u/Randomgirl)\
**Replies:** 17\
**Last updated:** [December 14, 2021, 4:50pm UTC](https://discussion.livingwithpsoriaticarthritis.org/t/cosentyx-i-think-it-is-working/10863 "2021-12-14T16:50:03Z")

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One photo was taken in August, and the other after my workout tonight. I can see a difference! I didn’t have sausage ties, I had sausage FOOT! I’m 2 doses into my loading doses (just took the 3rd tonight. So far I’ve ha…

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## [Adverse reaction to Enbrel](https://discussion.livingwithpsoriaticarthritis.org/t/adverse-reaction-to-enbrel/7806)

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**Author:** [@Kmwestmo](https://discussion.livingwithpsoriaticarthritis.org/u/Kmwestmo)\
**Replies:** 29\
**Last updated:** [August 20, 2021, 12:23pm UTC](https://discussion.livingwithpsoriaticarthritis.org/t/adverse-reaction-to-enbrel/7806 "2021-08-20T12:23:52Z")

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Started enbrel on a Friday. Did initial shot in right thigh at rhumetologist office. Went well. Next Friday came and time to do second injection. Did it in left thigh. Went well. Woke up the next Monday scratching my lef…

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## [Time for another Biologic](https://discussion.livingwithpsoriaticarthritis.org/t/time-for-another-biologic/10678)

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**Author:** [@yoamojesus2](https://discussion.livingwithpsoriaticarthritis.org/u/yoamojesus2)\
**Replies:** 3\
**Last updated:** [May 19, 2021, 7:28am UTC](https://discussion.livingwithpsoriaticarthritis.org/t/time-for-another-biologic/10678 "2021-05-19T07:28:38Z")

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Hi Everyone, the Cimzia has stopped working so, any suggestions? I’ve been on Enbrel, Stelara, Xeljanz, Otezla-there might be more but those are the ones I remember! I’ve been on several DMARD/biologic cocktails since 20…

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## [Guide to MTX according to Lamb's experience](https://discussion.livingwithpsoriaticarthritis.org/t/guide-to-mtx-according-to-lambs-experience/8535)

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**Author:** [@tntlamb](https://discussion.livingwithpsoriaticarthritis.org/u/tntlamb)\
**Replies:** 20\
**Last updated:** [April 22, 2021, 2:10am UTC](https://discussion.livingwithpsoriaticarthritis.org/t/guide-to-mtx-according-to-lambs-experience/8535 "2021-04-22T02:10:54Z")

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This isn’t medical advice BUT my experience with what has proven to be one of my favorite meds. IF you are taking it in pill form bad things are more likley to happen as it goes through the GI system. That is the caus…

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## [What do you do with you're unused pre-filled injectors?](https://discussion.livingwithpsoriaticarthritis.org/t/what-do-you-do-with-youre-unused-pre-filled-injectors/10556)

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**Author:** [@Zananne](https://discussion.livingwithpsoriaticarthritis.org/u/Zananne)\
**Replies:** 6\
**Last updated:** [April 22, 2021, 12:54am UTC](https://discussion.livingwithpsoriaticarthritis.org/t/what-do-you-do-with-youre-unused-pre-filled-injectors/10556 "2021-04-22T00:54:34Z")

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In November 2019 my Doc put me on Taltz and shortly after the 2nd dose I got a pretty nasty fungal infection on my foot and … other places … Anyway, I got that cleared up and started again. But after 4 or five months I h…

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## [Biologics side effects](https://discussion.livingwithpsoriaticarthritis.org/t/biologics-side-effects/10481)

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**Author:** [@Barryjohn](https://discussion.livingwithpsoriaticarthritis.org/u/Barryjohn)\
**Replies:** 23\
**Last updated:** [February 19, 2021, 2:27am UTC](https://discussion.livingwithpsoriaticarthritis.org/t/biologics-side-effects/10481 "2021-02-19T02:27:03Z")

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Hello, Does anyone experience any side effects from taking biologics. I have been taking benepali (an enbrel biosimilar) for about 2 years now. Recently i have been getting throat issues. If i drink alcohol (even a sma…

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## [Biologics and high blood pressure](https://discussion.livingwithpsoriaticarthritis.org/t/biologics-and-high-blood-pressure/4400)

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**Author:** [@clipclop](https://discussion.livingwithpsoriaticarthritis.org/u/clipclop)\
**Replies:** 29\
**Last updated:** [November 5, 2020, 7:10am UTC](https://discussion.livingwithpsoriaticarthritis.org/t/biologics-and-high-blood-pressure/4400 "2020-11-05T07:10:25Z")

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Hi folks! It has been awhile since I have posted. I have been on three different biologics in the past year. Enbrel stopped working after 1.5 years, Humira (6 months) forget about it, Cimzia for 2 months. The Cimzia h…

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## [Painfull Taltz injection](https://discussion.livingwithpsoriaticarthritis.org/t/painfull-taltz-injection/10373)

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**Author:** [@sbender](https://discussion.livingwithpsoriaticarthritis.org/u/sbender)\
**Replies:** 5\
**Last updated:** [September 7, 2020, 8:30pm UTC](https://discussion.livingwithpsoriaticarthritis.org/t/painfull-taltz-injection/10373 "2020-09-07T20:30:52Z")

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Hi All, Anyone out there on Taltz? just wondering if you experience the injections as extremely painful?

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## [Anybody tried Taltz yet](https://discussion.livingwithpsoriaticarthritis.org/t/anybody-tried-taltz-yet/8348)

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**Author:** [@beckipastor](https://discussion.livingwithpsoriaticarthritis.org/u/beckipastor)\
**Replies:** 1\
**Last updated:** [September 6, 2020, 1:31pm UTC](https://discussion.livingwithpsoriaticarthritis.org/t/anybody-tried-taltz-yet/8348 "2020-09-06T13:31:40Z")

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I’m currently on methotrexate and it’s not really doing much. My dermatologist suggested Taltz. Apparently it addresses pathway 17a directly so has less immune suppression issues. I was diagnosed with breast cancer 2 we…

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## [Symponi infusion, now a second med](https://discussion.livingwithpsoriaticarthritis.org/t/symponi-infusion-now-a-second-med/9506)

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**Author:** [@Bern](https://discussion.livingwithpsoriaticarthritis.org/u/Bern)\
**Replies:** 3\
**Last updated:** [September 5, 2020, 12:39am UTC](https://discussion.livingwithpsoriaticarthritis.org/t/symponi-infusion-now-a-second-med/9506 "2020-09-05T00:39:44Z")

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I started Symponi infusions every 2 months last May after a decent 3 year run on Remacaide. In 8 years of dealing with Psa I have never been pain free. So NP wants to add oral Plaquenil to my regimen. Getting baseline ey…

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